Foundation of the Istituto Toscano Tumori

ITT Cancer Research – Apoptosis – Oncology

Neurohumoral response and Fas-ligand-induced apoptosis in peripheral blood of patients with acute ischemic stroke

Neurohumoral response and Fas-ligand-induced apoptosis in peripheral blood of patients with acute ischemic stroke

Goal: To determine an impact of the neurohumoral response on the severity and orientation of Fas-ligand-initiated processes within the acute interval of IS.
Materials and strategies: The examine included 155 sufferers with IS within the territory of the left and proper center cerebral arteries, the management group consisted of 28 folks. The Nationwide Institutes of Well being Stroke Scale (NIHSS), the Hospital Anxiousness and Melancholy Scale (HADS), and the Each day Life Stress scale had been used. Concentrations of sFas, sFasL, cortisol (Ok), adrenaline (A), norepinephrine (NE), adrenocorticotropic hormone (ACTH) within the blood plasma of sufferers with IS had been measured by enzyme-linked immunosorbent assay on days 1, 7 and 21 and as soon as within the management group. CD3CD95+ lymphocytes phenotyping was carried out utilizing circulate cytometry.
Outcomes and conclusion: The hypothalamic-pituitary-adrenal axis dominance is related to the activation of the apoptosis-inducing properties of peripheral blood within the first week after the IS onset and their lower in the direction of the top of the acute interval, which is clinically represented by the elevated ranges of hysteria and melancholy, an unfavorable consequence of the acute interval of IS.
gentaur
 
Polyclonal FKBP51 polyclonal antibody
APR15992G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FKBP51 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal Rtf1 polyclonal antibody
APR11187G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Rtf1 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal Rtf1 polyclonal antibody
APR11188G 0.1ml
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Rtf1 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal JARID2 polyclonal antibody
APR12450G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JARID2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal Med26 polyclonal antibody
APR12517G 0.05mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Med26 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal Med26 polyclonal antibody
APR12518G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Med26 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal MeCP2 polyclonal antibody
APR12525G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal MeCP2 polyclonal antibody
APR12526G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal MeCP2 polyclonal antibody
APR12527G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal AKR1B10 Polyclonal Antibody
APG01659G 0.1mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AKR1B10 Polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal PADI4 polyclonal antibody
APR08916G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PADI4 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal RARA polyclonal antibody
APR00370G 0.05ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RARA polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal ETO polyclonal antibody
APR00372G 0.05ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ETO polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal EzH2 polyclonal antibody
APR00373G 0.05mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EzH2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal BRD2 polyclonal antibody
APR00374G 0.05ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BRD2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal JMJD2c polyclonal antibody
APR00375G 0.05ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JMJD2c polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal BMI1 polyclonal antibody
APR00376G 0.05ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BMI1 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal SHH Polyclonal Antibody
APR00434G 0.1mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SHH Polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal ETO polyclonal antibody
APR00435G 0.1ml
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ETO polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal EZH2 polyclonal antibody
APR00436G 0.1ml
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EZH2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal RARA polyclonal antibody
APR00437G 0.1ml
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RARA polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal MYH11 polyclonal antibody
APR00438G 0.1ml
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MYH11 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal EZH2 polyclonal antibody
APR00439G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EZH2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal p53K372me1 polyclonal antibody
APR00440G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human p53K372me1 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal CIITA polyclonal antibody
APR00442G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CIITA polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal p53 polyclonal antibody
APR00443G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human p53 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal CHD4 polyclonal antibody
APR00444G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CHD4 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal HDAC1 polyclonal antibody
APR00445G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HDAC1 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal Spt16 polyclonal antibody
APR00446G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Spt16 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal BRD2 polyclonal antibody
APR00447G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BRD2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal G9a polyclonal antibody
APR00448G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human G9a polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal Hira polyclonal antibody
APR00449G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Hira polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal JMJD2c polyclonal antibody
APR00450G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JMJD2c polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal SPI1 polyclonal antibody
APR00451G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human SPI1 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal BCL7C polyclonal antibody
APR00452G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BCL7C polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal LRWD1 polyclonal antibody
APR00455G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human LRWD1 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal LYDG10 polyclonal antibody
APR00456G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human LYDG10 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal BMI1 polyclonal antibody
APR00457G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human BMI1 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal KDM4D polyclonal antibody
APR00458G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human KDM4D polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal CHD4 polyclonal antibody
APR00459G 0.05mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CHD4 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal Spt16 polyclonal antibody
APR00460G 0.05mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Spt16 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal PIWIL2 polyclonal antibody
APR17846G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PIWIL2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal ACTL6B polyclonal antibody
AMM05547G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ACTL6B polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal ZMYND8 polyclonal antibody
AMM08559G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZMYND8 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal PML polyclonal antibody
AMR09397G 0.05mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PML polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal PPARG polyclonal antibody
AMR09459G 0.05mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPARG polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal PPARG polyclonal antibody
AMR09486G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PPARG polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal JARID2 polyclonal antibody
AMM06027G 0.05ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human JARID2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal MeCP2 polyclonal antibody
AMM06350G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal MeCP2 polyclonal antibody
AMM06351G 0.05mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MeCP2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal AntibodyP1 Polyclonal Antibody
ES11752-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against P1. This antibody is tested and validated for WB, ELISA, WB, ELISA
Polyclonal AntibodyP1 Polyclonal Antibody
ES11752-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against P1. This antibody is tested and validated for WB, ELISA, WB, ELISA
Polyclonal AntibodyP2 Polyclonal Antibody
ES10016-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against P2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA
Polyclonal AntibodyP2 Polyclonal Antibody
ES10016-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against P2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA
Polyclonal AntibodyP4 Polyclonal Antibody
ES10017-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against P4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA
Polyclonal AntibodyP4 Polyclonal Antibody
ES10017-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against P4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA
Polyclonal AntibodyP5 Polyclonal Antibody
ES4829-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against P5 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
Polyclonal AntibodyP5 Polyclonal Antibody
ES4829-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against P5 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
Polyclonal AntibodyP3 Polyclonal Antibody
ES6454-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against P3 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
Polyclonal AntibodyP3 Polyclonal Antibody
ES6454-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against P3 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA
Polyclonal TGF-beta3 Polyclonal Antibody
APG00008G 0.1mg
EUR 484.00
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human TGF-beta3 Polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal sRANK Ligand Polyclonal Antibody
APR00294G 0.1mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human sRANK Ligand Polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal FGF-1 Polyclonal Antibody
APR00423G 0.1mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human FGF-1 Polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal RFX-AP polyclonal antibody
APR00441G 0.05mg
EUR 528.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human RFX-AP polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal EIF2C1/2 polyclonal antibody
APR00453G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human EIF2C1/2 polyclonal . This antibody is tested and proven to work in the following applications:
Polyclonal Smc3K112/113ac polyclonal antibody
APR00454G 0.1ml
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Smc3K112/113ac polyclonal . This antibody is tested and proven to work in the following applications:
PARK2 Polyclonal Antibody
ABP55480-003ml 0.03ml
EUR 158.00
Description: A polyclonal antibody for detection of PARK2 from Human, Mouse, Rat. This PARK2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARK2 at AA range: 1-80
PARK2 Polyclonal Antibody
ABP55480-01ml 0.1ml
EUR 289.00
Description: A polyclonal antibody for detection of PARK2 from Human, Mouse, Rat. This PARK2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARK2 at AA range: 1-80
PARK2 Polyclonal Antibody
ABP55480-02ml 0.2ml
EUR 414.00
Description: A polyclonal antibody for detection of PARK2 from Human, Mouse, Rat. This PARK2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PARK2 at AA range: 1-80
T2R3 Polyclonal Antibody
ABP55482-003ml 0.03ml
EUR 158.00
Description: A polyclonal antibody for detection of T2R3 from Human. This T2R3 antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human T2R3 at AA range: 110-190
T2R3 Polyclonal Antibody
ABP55482-01ml 0.1ml
EUR 289.00
Description: A polyclonal antibody for detection of T2R3 from Human. This T2R3 antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human T2R3 at AA range: 110-190
T2R3 Polyclonal Antibody
ABP55482-02ml 0.2ml
EUR 414.00
Description: A polyclonal antibody for detection of T2R3 from Human. This T2R3 antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human T2R3 at AA range: 110-190
T2R16 Polyclonal Antibody
ABP55483-003ml 0.03ml
EUR 158.00
Description: A polyclonal antibody for detection of T2R16 from Human. This T2R16 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human T2R16 at AA range: 110-190
T2R16 Polyclonal Antibody
ABP55483-01ml 0.1ml
EUR 289.00
Description: A polyclonal antibody for detection of T2R16 from Human. This T2R16 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human T2R16 at AA range: 110-190
T2R16 Polyclonal Antibody
ABP55483-02ml 0.2ml
EUR 414.00
Description: A polyclonal antibody for detection of T2R16 from Human. This T2R16 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human T2R16 at AA range: 110-190
T2R1 Polyclonal Antibody
ABP55484-003ml 0.03ml
EUR 158.00
Description: A polyclonal antibody for detection of T2R1 from Human. This T2R1 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human T2R1 at AA range: 20-100
T2R1 Polyclonal Antibody
ABP55484-01ml 0.1ml
EUR 289.00
Description: A polyclonal antibody for detection of T2R1 from Human. This T2R1 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human T2R1 at AA range: 20-100
T2R1 Polyclonal Antibody
ABP55484-02ml 0.2ml
EUR 414.00
Description: A polyclonal antibody for detection of T2R1 from Human. This T2R1 antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human T2R1 at AA range: 20-100

Melatonin protects INS-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity

 

Introduction: Melatonin is a hormone often known as having very sturdy anti-oxidant property. Senescence is a organic state characterised by the lack of cell replication and the adjustments consisting of a pro-inflammatory phenotype, resulting in Senescence Related Secretory Phenotype (SASP) which is now thought to be one of many basic processes of many degenerative ailments. Elevated cell division depend induces cell senescence through DNA harm in response to elevated Reactive Oxygen Species (ROS). We needed to check whether or not melatonin may scale back apoptosis and stress induced untimely pancreatic β-cell senescence induced by glucotoxicity and glucolipotoxicity.
Supplies and technique: Cultured rodent pancreatic β-cell line (INS-1 cell) was used. Glucotoxicity (HG: hyperglycemia) and glucolipotoxicity (HGP: hyperglycemia with palmitate) had been induced by hyperglycemia and the addition of palmitate. The levels of the senescence had been measured by SA-β-Gal and P16lnk4A staining together with the adjustments of cell viabilities, cell cycle-related protein and gene expressions, endogenous anti-oxidant protection enzymes, and Glucose Stimulated Insulin Secretion (GSIS), earlier than and after melatonin therapy.
Outcomes: Cultured INS-1 cells in HG and HGP circumstances revealed accelerated senescence, elevated apoptosis, cell cycle arrest, compromised endogenous anti-oxidant protection, and impaired glucose-stimulated insulin secretion. Melatonin decreased apoptosis and expressions of proteins associated to senescence, enhance the endogenous anti-oxidant protection, and improved glucose-stimulated insulin secretion.
Conclusion: Melatonin protected pancreatic β-cell from apoptosis, decreased expressions of the markers associated to the accelerated senescence, and improved the organic deteriorations induced by glucotoxicity and glucolipotoxicity.
Key phrases: Melatonin; Senescence; glucolipotoxicity; glucotoxicity; pancreatic β-cell.
  • Diazinon (DZN) is an organophosphate insecticide that impacts the liver adversely. Ginger displays antioxidant properties. We investigated the hepatoprotective results of an ethanolic extract of ginger root on DZN induced hepatotoxicity.

Recombinant Epstein-Barr Apoptosis regulator BHRF1 Protein, His, E.coli-1mg
QP7005-1mg 1mg
EUR 2531.00

Recombinant Epstein-Barr Apoptosis regulator BHRF1 Protein, His, E.coli-200ug
QP7005-200ug 200ug
EUR 1224.00

Recombinant Epstein-Barr Apoptosis regulator BHRF1 Protein, His, E.coli-500ug
QP7005-500ug 500ug
EUR 1614.00

Recombinant Epstein-Barr Apoptosis regulator BHRF1 Protein, His, E.coli-50ug
QP7005-50ug 50ug
EUR 473.00

Epstein-Barr virus Epstein-Barr nuclear antigen 3 (EBNA3)
1-CSB-EP319032EFA
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 3 (EBNA3),partial expressed in E.coli

Epstein-Barr virus Epstein-Barr nuclear antigen 1 (EBNA1)
1-CSB-EP365878EFA
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 1(EBNA1),partial expressed in E.coli

Epstein-Barr virus Epstein-Barr nuclear antigen 2 (EBNA2)
1-CSB-YP718162EEZ(A4)
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Epstein-Barr virus Epstein-Barr nuclear antigen 2(EBNA2),partial expressed in Yeast

Epstein-Barr Virus (EBV) Antibody
abx021696-1mg 1 mg
EUR 1156.00

Epstein-Barr Virus (EBV) Antibody
abx021699-1mg 1 mg
EUR 1156.00

Epstein-Barr Virus (EBV) Antibody
abx021702-1mg 1 mg
EUR 1156.00

Epstein-Barr Virus Nuclear Antigen
abx670096-01mg 0.1 mg
EUR 1191.00

Anti-Epstein Barr Virus antibody
STJ16100364 1 mL
EUR 754.00

Recombinant Human Epstein Barr Virus Induced 3
7-00256 2µg Ask for price

Recombinant Human Epstein Barr Virus Induced 3
7-00257 10µg Ask for price

Recombinant Human Epstein Barr Virus Induced 3
7-00258 1mg Ask for price

Recombinant Mouse Epstein Barr Virus Induced 3
7-00262 2µg Ask for price

Recombinant Mouse Epstein Barr Virus Induced 3
7-00263 10µg Ask for price

Recombinant Mouse Epstein Barr Virus Induced 3
7-00264 1mg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p18
7-07795 100µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p18
7-07796 500µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p18
7-07797 1000µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p23
7-07804 100µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p23
7-07805 500µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p23
7-07806 1000µg Ask for price

Epstein-Barr virus EBNA-1 recombinant antigen
8916 100 ug
EUR 615.50
Description: This is Epstein-Barr virus EBNA-1 recombinant antigen for ELISA,WB.

Recombinant Epstein–Barr Virus P23, GST-tagged
DAG511 1mg
EUR 1112.00

Epstein-Barr Virus (EBV) Antibody (FITC)
abx021698-100ug 100 ug
EUR 732.00

Mouse antibody for Epstein-Barr virus
0223 100 ug
EUR 359.94
Description: This is Mouse monoclonal FITC conjugated antibody against Epstein-Barr virus gp 250/350 for WB, ELISA.

Epstein-Barr virus Glycoprotein BDLF3 (BDLF3)
1-CSB-EP365881EFA1
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Epstein-Barr virus Glycoprotein BDLF3(BDLF3),partial expressed in E.coli

Anti-Human Epstein-Barr Virus antibody
STJ16100457 1 mL
EUR 240.00

Anti-Epstein-Barr virus LMP antibody
STJ16100853 1 mL
EUR 964.00

Recombinant Epstein-Barr Virus (HHV-4) Mosaic EBNA1
7-07786 100µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) Mosaic EBNA1
7-07787 500µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) Mosaic EBNA1
7-07788 1000µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) Early Antigen
7-07792 100µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) Early Antigen
7-07793 500µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) Early Antigen
7-07794 1000µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p18 GST
7-07798 100µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p18 GST
7-07799 500µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p18 GST
7-07800 1000µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) Mosaic p18
7-07801 100µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) Mosaic p18
7-07802 500µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) Mosaic p18
7-07803 1000µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p23 His
7-07807 100µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p23 His
7-07808 500µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) p23 His
7-07809 1000µg Ask for price

Recombinant Epstein-Barr virus p18 antigen, Biotin-conjugated
DAG2699 1mg
EUR 1495.00

Recombinant Epstein Barr Virus Induced Protein 3 (EBI3)
4-RPD206Hu01
  • EUR 512.16
  • EUR 240.00
  • EUR 1645.60
  • EUR 615.20
  • EUR 1130.40
  • EUR 406.00
  • EUR 3964.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Epstein Barr Virus Induced Protein 3 expressed in: E.coli

Recombinant Epstein Barr Virus Induced Protein 3 (EBI3)
4-RPD206Mu01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Epstein Barr Virus Induced Protein 3 expressed in: E.coli

Human Epstein-Barr Virus (EBV) ELISA Kit
abx054176-96tests 96 tests
EUR 668.00

Goat polyclonal antibody for Epstein-Barr virus
291 1 ml
EUR 283.81
Description: This is goat polyclonal antibody against Epstein-Barr virus p18 for WB, ELISA.

Mouse antibody for Epstein-Barr virus VCA
231 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Epstein-Barr virus VCA for WB, ELISA.

Goat polyclonal antibody for Epstein-Barr virus
271 1 ml
EUR 283.81
Description: This is goat polyclonal antibody against Epstein-Barr virus EBNA-1 for WB, ELISA.

Goat polyclonal antibody for Epstein-Barr virus
277 1 ml
EUR 300.13
Description: This is Biotin conjugated goat polyclonal antibody against Epstein-Barr virus EBNA-1 for WB, ELISA.

Goat polyclonal antibody for Epstein-Barr virus
3714 1 ml
EUR 321.88
Description: This is HRP conjugated goat polyclonal antibody against Epstein-Barr virus p18 for WB, ELISA.

Epstein-Barr Virus (HHV-4) p18 Protein
20-abx260115
  • EUR 885.00
  • EUR 342.00
  • EUR 1372.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Epstein-Barr Virus (HHV-4) p23 Protein
20-abx260116
  • EUR 885.00
  • EUR 342.00
  • EUR 1372.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Epstein-Barr Virus (HHV-4) EBNA1 Protein
20-abx260340
  • EUR 1121.00
  • EUR 467.00
  • EUR 1970.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Epstein-Barr Virus (HHV-4) p18 Protein
20-abx260341
  • EUR 1121.00
  • EUR 467.00
  • EUR 1970.00
  • 0.5 mg
  • 100 ug
  • 1 mg

Epstein-Barr Virus Induced 3 (EBI3) Antibody
abx232615-100ug 100 ug
EUR 551.00

Epstein-Barr Virus Induced 3 (EBI3) Antibody
abx432634-200ul 200 ul
EUR 286.00

Epstein-Barr virus Envelope glycoprotein B (gB)
1-CSB-EP355975EFA
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Epstein-Barr virus Envelope glycoprotein B(gB),partial expressed in E.coli

Epstein-Barr virus Envelope glycoprotein L (gL)
1-CSB-EP355982EFA
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Epstein-Barr virus Envelope glycoprotein L(gL) expressed in E.coli

Epstein-Barr virus Envelope glycoprotein GP350 (BLLF1)
1-CSB-EP360986EFA
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Epstein-Barr virus Envelope glycoprotein GP350(BLLF1),partial expressed in E.coli

Epstein-Barr virus Envelope glycoprotein H (gH)
1-CSB-EP365883EFA
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Epstein-Barr virus Envelope glycoprotein H(gH),partial expressed in E.coli

Epstein Barr Virus NA1 IgA ELISA Kit
DEIA1030 96T
EUR 556.00
Description: For the qualitative determination of IgA class antibodies against Epstein Barr Virus in Human serum or plasma. It is intended for diagnosing and monitoring of patients related to infection by Epstein Barr Virus.

Epstein Barr Virus Zta IgA ELISA Kit
DEIA1034 96T
EUR 556.00
Description: For the qualitative determination of IgA class antibodies against Epstein Barr Virus in Human serum or plasma. It is intended for diagnosing and monitoring of patients related to infection by Epstein Barr Virus.

Recombinant Human Epstein Barr Virus Induced 3, His Tag
7-00259 2µg Ask for price

Recombinant Human Epstein Barr Virus Induced 3, His Tag
7-00260 10µg Ask for price

Recombinant Human Epstein Barr Virus Induced 3, His Tag
7-00261 1mg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) EBNA1, His Tag
7-07789 100µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) EBNA1, His Tag
7-07790 500µg Ask for price

Recombinant Epstein-Barr Virus (HHV-4) EBNA1, His Tag
7-07791 1000µg Ask for price

EBI3 Epstein Barr Virus Induced 3 Mouse Recombinant Protein
PROTO35228 Regular: 10ug
EUR 317.00
Description: EBI3 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids and having a molecular mass of 22.9kDa. ;The Murine EBI3 is purified by proprietary chromatographic techniques.

EBI3 Epstein Barr Virus Induced 3 Human Recombinant Protein
PROTQ14213 Regular: 10ug
EUR 317.00
Description: EBI3 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 209 amino acids fragment (21-229) having a molecular weight of 23.3kDa. ;The EBI3 is purified by proprietary chromatographic techniques.

EBI3 Epstein Barr Virus Induced 3 Macaque Recombinant Protein
PROTQ14213-2 Regular: 20ug
EUR 317.00
Description: EBI3 Macaque Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids and having a molecular mass of 23.4kDa. The EBI3 is purified by proprietary chromatographic techniques.

Mouse antibody for Epstein-Barr virus Bcl-2
235 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Epstein-Barr virus Bcl-2 for WB, ELISA.

Mouse antibody for Epstein-Barr virus EA-D
261 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Epstein-Barr virus EA-D for WB, ELISA.

Mouse antibody for Epstein-Barr virus EBNA-1
212 100 ug
EUR 321.88
Description: This is purified Mouse monoclonal antibody against Epstein-Barr virus EBNA-1 for WB, ELISA.

Human Epstein-Barr Virus Antibody (IgG) ELISA Kit
abx159186-96tests 96 tests
EUR 739.00
  • We measured complete phenolics and flavonoids within the hydroalcoholic extract. We used Wistar rats divided into 4 teams: management, 100 mg/kg/day ginger by gavage, 10 mg/kg/day DZN intraperitoneally, and ginger + DZN group handled with ginger 1 h earlier than DZN. All therapies had been for 30 consecutive days. Sooner or later after the final therapy, we evaluated oxidative stress parameters, serum biochemistry, histopathology and immunohistochemistry. The ginger extract contained 101.33 ± 2.73 mg complete flavonoid and 237.9 ± Three mg complete phenolic content material/g dry ginger plant roots.

 

  • We discovered that DZN elevated oxidative stress considerably. Histopathology of the liver tissue was in step with elevated AST, ALT, and ALP. Ginger extract therapy diminished oxidative stress and improved histopathology. DZN elevated caspase-Three immunoreactivity and ginger extract diminished it. Ginger extract exhibited hepatoprotective results in opposition to DZN induced hepatic harm owing to its antioxidant and anti-apoptotic exercise.